Biocytogen 

Animal Models and Cell Lines

>Cre mouse models

B-Col2a1-iCre mice

The Col2a1 gene encodes the alpha-1 chain of type II Collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye.

B-Col2a1-iCre mice

(C57BL/6-Col2a1tm1(iCre)/Bcgen)

Gene Targeting Strategy

B-Col2a1-iCre mice.png


Description

The Col2a1 gene encodes the alpha-1 chain of type II Collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. In this strain, Cre recombinase expression is under the control of Col2a1 promoter in a chondrocyte-specific pattern. When crossed with a strain containing a loxP site-flanked sequence of interest, Cre-mediated recombination results in deletion of the flanked sequence in Col2a1 expressing cells.


Phenotype

Mice hemizygous for Col2a1iCre gene are viable and fertile without any physical abnormalities.


(B-EM-002) B-Col2a1-iCre mice

 


 

【Return list】
* Contact Name
* Quantity
Telephone No.
Email
* Shipping address
Verification code captcha

© 2018 Beijing Biocytogen Co., Ltd. All rights reserved. Technical support: fast help cloud
in the section of your HTML pages