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B-Drd2-Cre rats

The Drd2 gene encodes dopamine receptor D2. In this strain, Cre recombinase expression is under the control of Drd2 promoter.

B-Drd2-Cre rats

(SD-Drd2tm1(Cre)/Bcgen)

Gene Targeting Strategy

B-Drd2-Cre rats.png

Description

The Drd2 gene encodes dopamine receptor D2. In this strain, Cre recombinase expression is under the control of Drd2 promoter. When crossed with a strain containing a loxP site-flanked sequence of interest, Cre-mediated recombination results in deletion of the flanked sequence in Drd2 expressing cells.

Phenotype

Rats hemizygous for Drd2Cre gene are viable and fertile without any physical abnormalities.

 (B-CR-003) B-Drd2-Cre rats

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