Biocytogen 

Animal Models and Cell Lines

>Double Humanized Immune-Checkpoint Mice

B-hPD-L1/h4-1BB mice

Basic characteristics

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Targeting strategy


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Protein expression analysis


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Fig 1. Splenocytes from B-hPD-L1/h4-1BB mice were analyzed by flow cytometry.

m4-1BB+ cells were detectable in the WT C57BL/6 mice, while h4-1BB+ cells were detectable in the homozygous B-hPD-L1/h4-1BB mice.



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Fig 2. Splenocytes from B-hPD-L1/h4-1BB mice were analyzed by flow cytometry.

mPD-L1+ cells were detectable in the WT C57BL/6 mice, while hPD-L1+ cells were detectable in the homozygous B-hPD-L1/h4-1BB mice.


 

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