Biocytogen 

Gene Targeting Services

>ESC Based Gene Gene KO/KI Targeting



Knockin mouse models introduce mutant or exogenous gene (s) into a specific locus on the mouse genome to mimic genetic diseases or monitorgene expression with reporter genes (e.g. EGFP, mRFPmCherry, YFP, LacZ, Flag, etc.). 

Knockin mouse models introduce mutant or exogenous gene (s) into a specific locus on the mouse genome to mimic genetic diseases or monitorgene expression with reporter genes (e.g. EGFP, mRFP, mCherry, YFP, LacZ, Flag, etc.). The gene reporter mouse models are also used to construct phylogenetictrees for cell developmentstudies. Replacement of the endogenous gene with a reporter can simultaneously achieve gene knockoutand knockin in the same mouse model.

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