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Cre工具小鼠列表
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B-Ucp1-iCre 敲进小鼠(B-Ucp1-iCre mice)
Ucp1 (uncoupling protein 1 ) 编码解偶联蛋白1,是一种跨膜蛋白表达于褐色脂肪组织的线粒体膜。B-Ucp1-iCre小鼠是将iCre序列通过ES同源重组技术插入到Ucp1基因下游。
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B-Col10a1-iCre敲进小鼠 (B-Col10a1-iCre mice)
Col10a1 (ollagen, type X, alpha 1)在软骨中表达短链小胶原蛋白。对软骨的行程至关重要。B-Col10a1-iCre小鼠是将iCre序列通过ES同源重组技术插入到Col10a1基因下游。
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B-Tnfrsf11a-iCre敲进小鼠 (B-Tnfrsf11a(RANK)-iCre mice)
Tnfrsf11a (tumor necrosis factor receptor superfamily, member 11a, NFKB activator)编码核因子κb激活受体。B-Tnfrsf11a(RANK)-iCre小鼠是将iCre序列通过ES同源重组技术插入到Tnfrsf11a(RANK)基因下游。
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B-Oxr1-iCreERT2敲进小鼠 (B-Oxr1-iCreERT2 mice)
Oxr1 (oxidation resistance 1)基因编码抗氧化蛋白1,其功能主要是防护氧化损伤。B-Oxr1-iCreERT2小鼠是将iCreERT2序列通过CRISPR/Cas9技术插入到Oxr1基因下游
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B-Syn1-iCre敲进小鼠(B-Syn1-iCre mice)
Syn1 (synapsin I ) 编码突触蛋白1,是一种神经元磷蛋白质与突触囊泡细胞膜形成相关。B-Syn1-iCre小鼠是将iCre序列通过CRISPR/Cas9技术插入到Syn1基因下游。
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