Animal Models and Cell Lines
> Cre Rat Models
B-Slc6a3(Dat1)-Cre rats The
Slc6a3 gene encodes the dopamine transporter (DAT), which mediates the active reuptake of dopamine from the synapse and is a principal regulator of dopaminergic neurotransmission.
B-Sncg(synuclein,gamma)-Cre rats The
Sncg gene encodes s a novel member of the synuclein gene family is principally expressed in the brain, particularly in the substantia nigra.
B-Slc6a2-Cre rats The
Slc6a2 gene encodes encodes a norepinephrine (noradrenaline) transporter, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis.
B-Nphs2(podocin)-CreERT2 rats The
Nphs2 gene encodespodocin, a protein that is expressed at the insertion of the slit diaphragm in the renal glomerulus.
B-Kit-CreERT2 rats The
Kit gene encodes the tyrosine kinase receptor KIT, KITand its ligand, KITLG, function in hematopoiesis, melanogenesis, and gametogenesis.
B-Drd2-Cre rats The
Drd2 gene encodes dopamine receptor D2. In this strain, Cre recombinase expression is under the control of Drd2 promoter.