B-Ifnar1 KO mice

C57BL/6N-Ifnar1tm1Bcgen/Bcgen • 111961

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B-Ifitm3 KO mice
B-Ifnar1 KO mice(129S2)

B-Ifnar1 KO mice

Catalog Number: 111961
Strain Name: C57BL/6N-Ifnar1tm1Bcgen/Bcgen
Strain Background: C57BL/6N
NCBI gene ID: 15975 (Mouse)
Aliases: Ifar; Ifrc; Ifnar; Infar
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B-Ifnar1 KO mice

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  • Targeting strategy
  • Phenotypic analysis

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      Targeting strategy

      Gene targeting strategy for B-Ifnar1 KO mice. The exons 1~11 and 3’UTR of mouse Ifnar1 gene were knocked out in B-Ifnar1 KO mice.

      Protein expression analysis
      IFNAR1 expression analysis in wild-type C57BL/6N and B-Ifnar1 KO mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6N and B-Ifnar1 KO mice. Mouse IFNAR1 was detectable in B cells, T cells, NK cells, DC cells, monocytes, macrophages and granulocytes of wild-type mice, but not in B-Ifnar1 KO mice.
      * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-Ifnar1 KO mice] (Cat# 111961) was purchased from Biocytogen.