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B-hPD-1/hOX40 mice

2017-08-04 13:44:34.0

Strain name: C57BL/6-Pdcd1tm1(hPDCD1)Tnfrsf4tm1(hTNFRSF4)/Bcgen

Appearance: Black

Related genes: PD-1(Programmed death-1)

                         Tnfrsf4Tumor necrosis factor receptor superfamily, member 4, also known as OX40


Protein expression analysis:

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Fig 1. Splenocytes from both wild type (WT) C57BL/6 and homozygous B-hPD-1/hOX40 mice were analyzed by flow cytometry. Mouse OX40+ T cells were detected in the WT C57BL/6 mice, while human OX40+ T cells were detected in the homozygous B-hPD-1/hOX40 mice.


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Fig 2. Splenocytes from both wild type (WT) C57BL/6 and homozygous B-hPD-1/hOX40 mice were analyzed by flow cytometry. Mouse PD-1+ T cells were detected in the WT C57BL/6 mice, while human PD-1+ T cells were detected in the homozygous B-hPD-1/hOX40 mice.



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