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B-hPD-1/hPD-L1 mice

2017-08-04 13:51:07.0

Strain name: C57BL/6-Pdcd1tm1(hPDCD1)Cd274tm1(hCD274)/Bcgen

Appearance: Black

Related genes: PD-1(Programmed death-1)

                            PD-L1 (Programmed cell death ligand-1also known as B7-H1, CD274)


Protein expression analysis:

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Fig 1. Splenocytes from both wild type (WT) C57BL/6 and homozygous B-hPD-1/hPD-L1 mice were analyzed by flow cytometry. Mouse PD-L1+ T cells were detected in the WT C57BL/6 mice, while human PD-L1+ T cells were detected in the homozygous B-hPD-1/hPD-L1 mice.


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Fig 2. Splenocytes from both wild type (WT) C57BL/6 and homozygous B-hPD-1/hPD-L1 mice were analyzed by flow cytometry. Mouse PD-1+ T cells were detected in the WT C57BL/6 mice, while human PD-1+ T cells were detected in the homozygous B-hPD-1/hPD-L1 mice.



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