RenMab™ Mouse Brochure
Biocytogen has developed a fully human antibody mouse (RenMab™ Mouse), whose genes that encode entire antibody variable regions are replace in situ by human Ig heavy chain and κ light chain through Mb-scale chromosome engineering technology. RenMab™ Mouse provides an efficient platform for fully human antibody generation, characterization, therapeutic antibody discovery, and rapid in vivo efficacy screening.
Highlights of RenMab™ Mouse:
- Developed using Biocytogen’s unique Mb-scale chromosome engineering technology
- Variable regions of heavy chain and κ light chain are replaced by human counterparts in situ
- Constant region remains mouse to ensure proper B cell development
- Normal antibody immune responses to antigens
- A highly diverse repertoire of fully human antibody variable regions through V(D)J recombination
To Learn more, please fill out the form to download the brochure.