RenMab™ Mouse Brochure
Biocytogen has developed a fully human antibody mouse (RenMab™ Mouse), whose genes that encode entire antibody variable regions are replace in situ by human Ig heavy chain and κ light chain through Mb-scale chromosome engineering technology. RenMab™ Mouse provides an efficient platform for fully human antibody generation, characterization, therapeutic antibody discovery, and rapid in vivo efficacy screening.
Highlights of RenMab™ Mouse:
- An intact immune system compared to wild-type mouse
- Full human VDJ expression in the variable domains of heavy chain and kappa light chain genes
- Fully human antibody repertoire as shown by CDR3 analysis
- Highly similar immune responses compared to wild-type mouse
To Learn more, please fill out the form to download the brochure.