Director for Disease Model Development
Location: Boston, MA
Employment Type: Full Time
We are currently seeking a highly self-motivated individual with a proven track record to lead our preclinical pharmacology using various mouse disease models and to design and execute various in vivo projects according to our clients’ specific needs. Experience working in multiple fields of preclinical pharmacology, including immunology, oncology, autoimmune disease & inflammation, infection, neurology, ophthalmology, cardiology, and solid organ transplantation, is a must. This position requires a highly self-motivated individual with a creative problem-solving skill who can work effectively to meet our clients’ dynamic requirements and stringent timelines.
- Lead the preclinical in vivo pharmacology disease model group to design and execute various animal model studies based on clients’ needs.
- Establish classic animal models for human diseases using various methods including but not limited to surgery and chemically-induced. The models to be established might cross different preclinical fields, such as RA, EAE, asthma, orthotopic cancer models, heart or kidney transplant, myocardial infarction, stroke and more.
- Train group members to excellence in special tubing and instillation techniques that will allow drug candidate to be delivered to particular areas in the experimental animals. For example, intra-cerebroventricular, spinal cord, intra-trachea, intra-hepatic portal vein, subretinal, intra-vitreous, in utero fetal cell transplantation and more.
- Independently execute in vivo experiments, generate raw data, perform data analysis, and interpret experimental results.
- Manage internal resource allocation and external collaborations
- Participate and present data during internal and external research meetings and interface with cross-functional groups.
- Participate in the training of in vivo personnel to proficiency.
- Follow laboratory safety guidelines and practices.
Required skills and Experience:
- MD or PhD degree in biological science with significant relevant biotech/pharmaceutical industry experience (12+ years)
- Strong medical background and knowledge to understand human clinical diseases in autoimmune, cancer, neurology, solid organ transplantation, cardiology, and ophthalmology.
- Strong hands-on skills to manipulate surgical microscope and stereotaxic to perform micro-surgery.
- Demonstrated ability to work independently and collaboratively in a cross-functional environment.
- Strong ability to prioritize and manage multiple projects simultaneously and manage a team of scientists and research associates in a biopharmaceutical setting.
- Must have excellent troubleshooting, organization, and planning skills with the ability to work under timeline in a fast-paced environment.
- Good communication and presentation skills in English are required.
- Highly self-motivated and hardworking.
BIOCYTOGEN is an Equal Opportunity Employer. Employment opportunities at BIOCYTOGEN BOSTON CORP are based upon one’s qualifications and capabilities to perform the essential functions of a particular job. All employment opportunities are provided without regard to race, color religion, sex, national origin, ancestry, age, sexual orientation, gender identity and expression, veteran status, military status, disability, mental illness, genetic information, or any other characteristic protected by law. This Equal Employment Opportunity policy governs all aspects of employment, including, but not limited to, recruitment, hiring, selection, job assignment, promotions, transfers, compensation, discipline, termination, layoff, access to benefits and training, and all other conditions and privileges of employment.
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