Research Scientist and Associate for in vivo Studies
Location: Boston, MA
Employment Type: Full Time
The primary responsibilities of the Research Scientist/Associate will be to establish and characterize conventional and innovative immuno-oncology and oncology animal models in our new Boston site. In addition, the incumbent will assist and perform ex vivo and in vitro cellular and/or biochemical assays to support model characterization.
- This hands-on position requires strong scientific training and laboratory skills in the immunology, immuno-oncology, and oncology.
- The incumbent will establish, characterize, and interpret immuno-oncology and oncology mouse models that include syngeneic, xenograft, genetically engineered mouse models, and human immune cell- and hematopoietic progenitor cell-engrafted murine models for pharmacological and pharmacodynamics studies.
- The incumbent is expected to work independently to perform and troubleshoot in vivo studies, and responsible for data collection, analysis, interpretation, and reporting. He/she will also work collaboratively with scientists throughout the company to introduce and apply the most effective and efficient technologies and techniques to quickly expand our model portfolio. Literature research, academic collaborations, and innovative thinking are additional key components of such effort.
- The incumbent will also collaborate and support ex vivo and in vitro investigations of such animal models using cellular and biochemical methodologies.
- The incumbent is expected to effectively communicate and present study results both at internal team and departmental meetings and to external scientific communities.
Required Skills and Experience:
- A/BS with over 5 years, M.S. with over 3 years, or Ph.D. graduate with 0-3 years’ academic or industry experience in biological sciences, immunology, immuno-oncology or oncology.
- Extensive relevant research experience using animal models as evidenced in publications is required. Experience with immuno-oncology models such as PBMC and CD34+ hematopoietic cell-engrafted immunodeficient mice is highly desirable. Experience with xenograft and/or PDX oncology models is very desirable.
- Expertise in handling small animals, drug administration, blood and tissue collections.
- Prior experience and knowledge in pharmacology and PK/PD is highly desirable.
- Expertise with primary immune or cancer cell preparation from blood or tissues is strongly preferred.
- Expertise in flow cytometry analysis, tissue culture, cellular and biochemical assays using primary and cultured cells, technologies in protein and RNA expression analysis is desired.
- Strong organizational skills and attention to details. Maintain research data and records with highest integrity.
- Collaborative team player. Be flexible and prioritize tasks based on team and company goals. Ability to multitask in fast-paced environment.
- Communicate effectively at all levels, within teams and with internal and external collaborators.
BIOCYTOGEN is an Equal Opportunity Employer. Employment opportunities at BIOCYTOGEN BOSTON CORP are based upon one’s qualifications and capabilities to perform the essential functions of a particular job. All employment opportunities are provided without regard to race, color religion, sex, national origin, ancestry, age, sexual orientation, gender identity and expression, veteran status, military status, disability, mental illness, genetic information, or any other characteristic protected by law. This Equal Employment Opportunity policy governs all aspects of employment, including, but not limited to, recruitment, hiring, selection, job assignment, promotions, transfers, compensation, discipline, termination, layoff, access to benefits and training, and all other conditions and privileges of employment.
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