The Utility of the Rosa26 Knock-in Mouse

November 19, 2019

The Rosa26 locus in the mouse genome is a “safe harbor” which allows researchers to express genes of interest. Different gene targeting technologies (embryonic stem cells; CRISPR) are used to make specific DNA insertions at the Rosa26 locus. The rationale for scientists to use Rosa26 and other key benefits to using this type of mouse […]

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