Festival of Biologics – USA

Festival of Biologics – USA

Join us at the The Festival of Biologics USA in San Diego, CA from March 20- 22! Learn more about our antibody discovery capabilities and humanized antibody mice. Our Beacon- and FACS-based screening services can identify hundreds, or even thousands, of single B cells that generate antibodies to your target in one day, so let us help you select the right platform for your antibody discovery project!

Dates: March 20th-22nd, 2023
Speaker: Dr. Li Hui, M.D./Ph.D.
Topic: Sourcing Fully Human Therapeutic Antibodies from Humanized Mice and Human PBMCs
Summary:

  • We have generated multiple strains of fully human antibody transgenic mice for therapeutic discovery. Antibody-secreting B cells from these mice undergo in vivo natural selection and affinity maturation, which improves the chance of clinical success compared to artificial humanized murine antibodies.
  • Our antibody discovery platform uses optimized immunization methods and high-throughput screening technologies to capture high-quality, fully human antibodies from immunized mice or human PBMCs for a streamlined downstream validation and selection process.

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