SITC2024: TAA antibody library and novel linker/payload BLD1102 for ADC, bispecific ADC and nanobody-drug conjugate development

SITC2024: TAA antibody library and novel linker/payload BLD1102 for ADC, bispecific ADC and nanobody-drug conjugate development

Summary:

• RenMice platforms including RenMab, RenLite, RenNano with KO strategy enable accelerated identification of fully human antibodies with increased diversity of antibody paratopes and species cross-reactivity
• “Plug & Play”: Off-the-shelf TAA antibody library on over 200 targets including monoclonal antibodies, mAbs with common light chain, heavy chain only antibodies from Biocytogen serve as building block for bi-/multi-specific antibodies, ADCs, cell therapies, and various modalities
• Novel ADC linker/payload BLD1102 facilitates ADC development