B-Camk2a-iCre-EGFP mice

March 9, 2023

Mice homozygous for the Camk2a-iCre are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. In this strain, iCre recombinase expression is under the control of Camk2a promoter. When crossed with a strain containing a loxP-site flanked sequence of interest, Cre-mediated recombination will result in deletion of the floxed […]

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B-Cx3cr1-iCreERT2-EGFP mice

March 9, 2023

Homozygous mice for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. In this strain, iCre/ERT2 fusion protein and EGFP expression is under the control of Cx3cr1 promoter. When crossed with a strain containing a loxP-site flanked sequence of interest, Cre-mediated recombination will result in […]

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B-Pgr-iCre mice

March 9, 2023

Homozygous mice for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. B-ROSA26-EGFP-DTA mice have STOP cassettes preventing expression of diphtheria toxin fragment A (DTA). DTA expression will be activated, if STOP cassettes are removed – resulting in the specific ablation of the cre-expressing cells. […]

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B-ROSA26-EGFP-DTA mice

March 9, 2023

Homozygous mice for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. B-ROSA26-EGFP-DTA mice have STOP cassettes preventing expression of diphtheria toxin fragment A (DTA). DTA expression will be activated, if STOP cassettes are removed – resulting in the specific ablation of the cre-expressing cells. […]

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B-Htr2c-iCre mice

March 9, 2023

TSerotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, modulating serotonergic neurotransmission in the central nervous system. In this strain, codon optimized Cre recombinase expression is under the control of Htr2c promoter. When crossed with a strain containing a loxP site-flanked sequence of interest, iCre-mediated recombination results in deletion of the flanked sequence in Htr2c expressing cells.

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B-Tagln-iCre mice

March 8, 2023

Heterozygous mice for the targeted mutation are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. In this strain, iCre recombinase expression is under the control of Tagln promoter. When crossed with a strain containing a loxP-site flanked sequence of interest, Cre-mediated recombination will result in deletion of the […]

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