B-hPD-1/hSIRPA/hCD47 Mice

Basic Information

Strain Name
C57BL/6-Pdcd1 tm1(PDCD1) Sirpa tm1(SIRPA) Cd47 tm1(CD47) /Bcgen
Stock Number
130562
Common Name
B-hPD-1/hSIRPA/hCD47 mice
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Related Genes
Pd-1 (Programmed death-1) ; CD47 (CD47 molecule) ; SIRPA (Signal regulatory protein alpha)
Species
C57BL/6
Appearance
Black
Genotypes
Homozygous

Targeting Strategy

B-hPD-1-hSIRPA-hCD47-Gene-Targeting

References

1. Nat Commun. 2017 Feb 6;8:14369. doi: 10.1038/ncomms14369.
2. EMBO J. 1992 Nov;11(11):3887-95.
3. PNAS July 2, 2013 110 (27) 11103-11108; doi: 10.1073/pnas.1305569110
4. Curr Opin Immunol. 2012 April ; 24(2): 225-232. doi:10.1016/j.coi.2012.01.010
5. Genes to Cells (2015) 20, 451–463 doi: 10.1111/gtc.12238

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