The exons 1-14 of mouse Alb gene that encode the full-length protein were replaced by human ALB exons 1-14 in B-hALB mice.
Protein expression analysis
Strain specific ALB expression analysis in heterozygous B-hALB mice by ELISA.
Serum was collected from C57BL/6 wild-type mice (+/+) and heterozygous B-hALB mice (H/+) analyzed by ELISA with species-specific ALB ELISA kit. Mouse ALB were both detectable in wild-type mice and heterozygous B-hALB mice. Human ALB was exclusively detectable in heterozygous B-hALB mice but not in wild-type mice. ND: not detected.