Basic Information
Strain name
C57BL/6N-Ccl11tm1(CCL11)/Bcgen
Common Name
B-hCCL11 mice
Background
C57BL/6N
Catalog Number
111404
Aliases
CCL11(SCYA11)
NCBI Gene ID
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Targeting strategy
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Gene targeting strategy for B-hCCL11 mice. The exons 1-3 of mouse Ccl11 gene that encode the full-length protein were replaced by human CCL11 exons 1-3 in B-hCCL11 mice.
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Protein expression analysis in serum
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Strain specific CCL11 expression analysis in homozygous B-hCCL11 mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hCCL11 mice (H/H), and analyzed by ELISA with species-specific CCL11 ELISA kit. Mouse CCL11 was detectable only in wild-type mice. Human CCL11 was detectable in homozygous B-hCCL11 mice but not in wild-type mice.
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Summary
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Protein expression analysis:
Human CCL11 was detectable in homozygous B-hCCL11 mice but not in wild-type mice, and mouse CCL11 was detectable only in wild-type mice.
