Basic Information

Strain Name
C57BL/6-Ccl22tm1(CCL22)/Bcgen
Common Name
B-hCCL22 mice
Background
C57BL/6J
Catalog number
110817
Related Genes
CCL22, A-152E5.1, ABCD-1, DC/B-CK, MDC, SCYA22, STCP-1, C-C motif chemokine ligand 22
NCBI Gene ID

mRNA expression analysis

Species-specific CCL22 gene expression analysis in wild-type and humanized B-hCCL22 mice by RT-PCR. Murine Ccl22 mRNA was detected in thymus isolated from wild-type mice, while human CCL22 mRNA was exclusively detected in homozygous B-hCCL22 (H/H) mice.

Protein expression analysis

Species-specific CCL22 protein expression analysis in wild-type and humanized B-hCCL22 mice by ELISA. Thymic homogenates were isolated from wild-type and homozygous B-hCCL22 (H/H) mice and analyzed using species-specific CCL22 ELISA kits. Murine CCL22 protein was detected in wild-type mice, while human CCL22 protein was exclusively detected in B-hCCL22 mice. Values are expressed as mean ± SEM. ND: not detectable.