Basic Information
Strain name
C57BL/6N-Fgf21tm1(FGF21)/Bcgen
Common Name
B-hFGF21 mice
Background
C57BL/6N
Catalog Number
112156
Aliases
FGF21, fibroblast growth factor 21
NCBI Gene ID
-
Gene targeting strategy
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Gene targeting strategy for B-hFGF21 mice. Exons 1-3 of mouse FGF21 gene that encode the full-length protein were replaced by human FGF21 exons 2-4 in B-hFGF21 mice.
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Protein expression analysis
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Strain specific FGF21 expression analysis in wild type (WT) mice and B-hFGF21 mice by ELISA. Serum was collected from WT mice (+/+) and homozygous B-hFGF21 mice (H/H) and analyzed by ELISA with FGF21 ELISA kit. Mouse FGF21 was detectable in WT mice (+/+).Human FGF21 was detectable in homozygous B-hFGF21 mice (H/H). Values are expressed as mean ± SEM.
