Basic Information
Strain Name
C57BL/6-Gfraltm1(GFRAL)/Bcgen
Common Name
B-hGFRAL mice
Background
C57BL/6
Catalog number
111202
Related Genes
GDNF family receptor alpha like, C6orf144, GRAL, UNQ9356, bA360D14.1
NCBI Gene ID
-
mRNA expression analysis
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Species-specific GFRAL gene expression analysis in wild-type and humanized B-hGFRAL mice by RT-PCR. Murine Gfral mRNA was detected in brain tissue isolated from wild-type mice (+/+), while human GFRAL mRNA was exclusively detected in homozygous B-hGFRAL (H/H) mice.
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Protein expression analysis
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Species-specific GFRAL protein expression analysis in wild-type and humanized B-hGFRAL mice. Ovarian and stomach tissues were isolated from wild-type C57BL/6 (+/+) and homozygous B-hGFRAL (H/H) mice and analyzed by western blot. GFRAL protein was detected in wild-type and B-hGFRAL mice due to the cross-reactivity of antibodies.
