Basic Information

Strain Name
C57BL/6-Grptm1(GRP)/Bcgen
Common Name
B-hIL18 mice
Background
C57BL/6J
Catalog number
111902
Aliases
GRP (BN, GRP-10, proGRP, preproGRP)
NCBI Gene ID

mRNA expression analysis

Species-specific GRP gene expression analysis in wild-type and humanized B-hGRP mice by RT-PCR. Murine Grp mRNA was detected in brain tissue isolated from wild-type mice (+/+), while human GRP mRNA was detected in B-hGRP mice.

Protein expression analysis

Species-specific GRP protein expression analysis in wild-type and humanized B-hGRP mice. Brain tissue was isolated from wild-type C57BL/6 (+/+) and homozygous B-hGRP (H/H) mice and analyzed by western blot using an anti-m/hGRP antibody. GRP protein was detected in wild-type and B-hGRP mice, due to the cross-reactive GRP antibody.