Basic Information
Strain name
C57BL/6-Il18bptm1(IL18BP)/Bcgen
Common name
B-hIL18BP mice
Background
C57BL/6
Catalog number
112360
Aliases
FVH; IL18BPa
NCBI Gene ID
-
Targeting strategy
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Gene targeting strategy for B-hIL18BP mice. The mouse Il18bp gene that encoding the full-length protein was replaced by human IL18BP counterpart gene sequence in B-hIL18BP mice.
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Protein expression analysis
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Strain specific IL18BP expression analysis in homozygous B-hIL18BP mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hIL18BP mice (H/H) and analyzed by ELISA with species-specific IL18BP ELISA kit. Mouse IL18BP was detectable in wild-type mice. Human IL18BP was exclusively detectable in homozygous B-hIL18BP mice but not in wild-type mice.
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Summary
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Protein expression analysis:
Human IL18BP was exclusively detectable in homozygous B-hIL18BP mice but not in wild-type mice.
