Basic Information
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mRNA expression analysis
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Species-specific SELE gene expression analysis in wild-type and double humanized B-hSELE/hSELL mice by RT-PCR. Murine Sele mRNA was detected in bladder cells isolated from wild-type C57BL/6 (+/+) mice, while human SELE mRNA was exclusively detected in homozygous B-hSELE/hSELL (H/H; H/H) mice.
Species-specific SELL gene expression analysis in wild-type and double humanized B-hSELE/hSELL mice by RT-PCR. Murine SELL mRNA was detected in splenocytes isolated from wild-type C57BL/6 (+/+) mice, while human SELL mRNA was exclusively detected in homozygous B-hSELE/hSELL (H/H; H/H) mice.
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Protein expression analysis
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Species-specific SELE protein expression analysis in double humanized B-hSELE/hSELL mice. Serum was collected from wild-type C57BL/6 (+/+) and homozygous B-hSELE/hSELL (H/H; H/H) mice and analyzed using species-specific SELE ELISA kits. Murine SELE protein was detected in wild-type mice, while human SELE protein was exclusively detected in B-hSELE/hSELL mice.
Species-specific SELL protein expression analysis in double humanized B-hSELE/hSELL mice. Serum was collected from wild-type C57BL/6 (+/+) and homozygous B-hSELE/hSELL (H/H; H/H) mice and analyzed using species-specific SELL ELISA kits. Murine SELL protein was detected in wild-type mice, while human SELL protein was exclusively detected in B-hSELE/hSELL mice.
