Basic Information

Strain Name
C57BL/6-Seletm1(SELE)Selltm1(SELL)/Bcgen
Common Name
B-hSELE/hSELL mice
Background
C57BL/6J
Catalog number
121056
Related Genes
SELE (ELAM; ESEL; CD62E; ELAM1; LECAM2; selectin-e); SELL(TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1)
NCBI Gene ID

mRNA expression analysis

Species-specific SELE gene expression analysis in wild-type and double humanized B-hSELE/hSELL mice by RT-PCR. Murine Sele mRNA was detected in bladder cells isolated from wild-type C57BL/6 (+/+) mice, while human SELE mRNA was exclusively detected in homozygous B-hSELE/hSELL (H/H; H/H) mice.

Species-specific SELL gene expression analysis in wild-type and double humanized B-hSELE/hSELL mice by RT-PCR. Murine SELL mRNA was detected in splenocytes isolated from wild-type C57BL/6 (+/+) mice, while human SELL mRNA was exclusively detected in homozygous B-hSELE/hSELL (H/H; H/H) mice.

Protein expression analysis

Species-specific SELE protein expression analysis in double humanized B-hSELE/hSELL mice. Serum was collected from wild-type C57BL/6 (+/+) and homozygous B-hSELE/hSELL (H/H; H/H) mice and analyzed using species-specific SELE ELISA kits. Murine SELE protein was detected in wild-type mice, while human SELE protein was exclusively detected in B-hSELE/hSELL mice.

Species-specific SELL protein expression analysis in double humanized B-hSELE/hSELL mice. Serum was collected from wild-type C57BL/6 (+/+) and homozygous B-hSELE/hSELL (H/H; H/H) mice and analyzed using species-specific SELL ELISA kits. Murine SELL protein was detected in wild-type mice, while human SELL protein was exclusively detected in B-hSELE/hSELL mice.