Basic Information

Strain Name
C57BL/6-Tektm1(TEK)/Bcgen
Common Name
B-hTEK mice
Background
C57BL/6J
Catalog number
111106
Related Genes
TEK receptor tyrosine kinase, CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
NCBI Gene ID

mRNA expression analysis

Species-specific TEK gene expression analysis in wild-type and humanized B-hTEK mice by RT-PCR. Murine Tek mRNA was detected in lung tissue isolated from wild-type (+/+) mice, while human TEK mRNA was exclusively detected in homozygous B-hTEK (H/H) mice.

Protein expression analysis

Species-specific TEK protein expression analysis in wild-type and humanized B-hTEK mice. Lung tissue was isolated from wild-type C57BL/6 (+/+) and homozygous B-hTEK (H/H) mice, and analyzed by flow cytometry using species-specific anti-TEK antibodies. Murine TEK protein was detected in wild-type mice, while human TEK protein was detected in both wild-type and B-hTEK mice due to the antibody cross-reactivity.