Basic Information

Strain name
C57BL/6-C5ar1tm1(C5AR1)/Bcgen
Common name
B-hC5AR1 mice
Background
C57BL/6J
Catalog number
110078
Related genes
C5A; C5AR; C5R1; CD88
NCBI Gene ID

Protein expression analysis

Protein expression analysis (spleen)

Species-specific C5AR1 protein expression analysis in wild-type and humanized B-hC5AR1 mice. Splenocytes were isolated from wild-type C57BL/6 (+/+) and homozygous B-hC5AR1 (H/H) mice, and analyzed by flow cytometry using species-specific anti-C5AR1 antibodies. Murine C5AR1 protein was detected in wild-type mice, while human C5AR1 protein was exclusively detected in B-hC5AR1 mice.

Protein expression analysis (bone marrow)

Species-specific C5AR1 protein expression analysis in wild-type and humanized B-hC5AR1 mice. Bone marrow was isolated from wild-type C57BL/6 (+/+) and homozygous B-hC5AR1 (H/H) mice, and analyzed by flow cytometry using species-specific anti-C5AR1 antibodies. Murine C5AR1 protein was detected in wild-type mice, while human C5AR1 protein was detected in B-hC5AR1 mice.