Basic Information

Strain name
C57BL/6-C5ar1tm1(C5AR1)/Bcgen
Common name
B-hC5AR1 mice
Background
C57BL/6
Catalog number
110078
Related genes
C5A; C5AR; C5R1; CD88
NCBI Gene ID

Details

Protein expression analysis(spleen)

Strain specific C5AR1 expression analysis in homozygous B-hC5AR1 mice by flow cytometry. Splenocytes were collected from WT and homozygous B-hC5AR1 (H/H) mice, and analyzed by flow cytometry with species-specific anti-C5AR1 antibody. C5AR1 was detectable in mouse spleen Dendritic cells, granulocytes and macrophages. Mouse C5AR1 was detectable in WT mice. Human C5AR1 was exclusively detectable in homozygous B-hC5AR1 but not WT mice.

Protein expression analysis(Bone marrow)

Strain specific C5AR1 expression analysis in homozygous B-hC5AR1 mice by flow cytometry. Bone marrow were collected from WT and homozygous B-hC5AR1 (H/H) mice, and analyzed by flow cytometry with species-specific anti-C5AR1 antibody. Mouse C5AR1 was detectable in WT mice. Human C5AR1 was exclusively detectable in homozygous B-hC5AR1 dendritic cells but not WT mice.