Basic Information

Strain Name
C57BL/6N-CB2tm1(CB2)/Bcgen
Common Name
B-hCB2 mice
Background
C57BL/6N
Catalog Number
111000
Alias
N/A
NCBI Gene ID

Targeting Strategy

Gene targeting strategy for B-hCB2 mice.

Exon 1 of mouse CB2 (encoding the full-length protein) was replaced by human CB2 exon 1 in B-hCB2 mice.

CB2 mRNA Expression

Strain specific analysis of CB2 gene expression in wild-type mice and B-hCB2 mice by RT-PCR. Mouse CB2 mRNA was detectable in splenocytes of wild-type mice (+/+). Human CB2 mRNA was detectable only in homozygous humanized B-hCB2  mice.

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