Basic Information
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Details
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Strain specific analysis of CXCR2 gene expression in WT and B-hCXCR2 mice by RT-PCR. Mouse Cxcr2 mRNA was detectable in splenocytes of wild-type (+/+) mice. Human CXCR2 mRNA was detectable only in H/H, but not in +/+ mice.
Protein expression analysis in Gr-1+ cells in spleen
Strain specific CXCR2 expression analysis in heterozygous B-hCXCR2 mice by flow cytometry. Splenocytes were collected from WT and heterozygous B-hCXCR2 (H/H) mice, and analyzed by flow cytometry with species-specific CXCR2 antibody. Mouse CXCR2 was detectable in WT mice and heterozygous B-hCXCR2. Human CXCR2 was exclusively detectable in heterozygous B-hCXCR2 but not WT mice.
Protein expression analysis in Gr-1+ cells in bone marrow
Strain specific CXCR2 expression analysis in heterozygous B-hCXCR2 mice by flow cytometry. Bone marrow were collected from WT and heterozygous B-hCXCR2 (H/H) mice, and analyzed by flow cytometry with species-specific CXCR2 antibody. Mouse CXCR2 was detectable in WT mice and heterozygous B-hCXCR2. Human CXCR2 was exclusively detectable in heterozygous B-hCXCR2 but not WT mice.
