Basic Information

Strain Name
C57BL/6-B2mtm1(B2M/HLA-G)/Bcgen
Common Name
B-hB2M/hHLA-G mice
Background
C57BL/6
Catalog number
111339
Related Genes
HLA-G
NCBI Gene ID

Protein expression analysis

Species-specific B2M protein expression analysis in wild-type and humanized B-hB2M/hHLA-G mice. Splenocytes were isolated from wild-type C57BL/6 (+/+) and heterozygous B-hB2M/hHLA-G (H/+) mice and analyzed by flow cytometry using species-specific anti-B2M antibodies. Murine B2M protein was detected in wild-type and B-hB2M/hHLA-G mice, while human B2M protein was only detected in B-hB2M/hHLA-G mice.

Species-specific HLA-G protein expression analysis in wild-type and humanized B-hB2M/hHLA-G mice. Splenocytes were isolated from wild-type C57BL/6 (+/+) and heterozygous B-hB2M/hHLA-G (H/+) mice and analyzed by flow cytometry using an anti-human HLA-G antibody. Human HLA-G protein was detected in B-hB2M/hHLA-G mice, but not in wild-type mice.