Basic Information
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Protein expression analysis
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Species-specific CD112 protein expression analysis in wild-type and double humanized B-hCD155/hCD112 mice. Spleen-derived dendritic cells and macrophages from peritoneal lavage fluid were isolated from wild-type C57BL/6 (+/+) and heterozygous B-hCD155/hCD112 (H/+) mice and analyzed by flow cytometry using species-specific anti-CD112 antibodies. Murine CD112 protein was detected in wild-type and heterozygous B-hCD155/hCD112 mice, while human CD112 protein was only detected in B-hCD155/hCD112 mice.
Species-specific CD155 protein expression analysis in wild-type and double humanized B-hCD155/hCD112 mice. Spleen-derived dendritic cells and macrophages from peritoneal lavage fluid were isolated from wild-type C57BL/6 (+/+) and heterozygous B-hCD155/hCD112 (H/+) mice and analyzed by flow cytometry using species-specific anti-CD155 antibodies. Murine CD155 protein was detected in wild-type and heterozygous B-hCD155/hCD112 mice, while human CD155 protein was only detected in B-hCD155/hCD112 mice.