Basic Information

Strain Name
C57BL/6-Cd155tm1(CD155)Nectin2tm1(NECTIN2)/Bcgen
Common Name
B-hCD155/hCD112 mice
Background
C57BL/6J
Catalog number
112005
Aliases
PVR, HVED, NECL5, Necl-5, PVS, TAGE4 CD112, HVEB, PRR2, PVRL2, PVRR2
NCBI Gene ID

Protein expression analysis

Species-specific CD112 protein expression analysis in wild-type and double humanized B-hCD155/hCD112 mice. Spleen-derived dendritic cells and macrophages from peritoneal lavage fluid were isolated from wild-type C57BL/6 (+/+) and heterozygous B-hCD155/hCD112 (H/+) mice and analyzed by flow cytometry using species-specific anti-CD112 antibodies. Murine CD112 protein was detected in wild-type and heterozygous B-hCD155/hCD112 mice, while human CD112 protein was only detected in B-hCD155/hCD112 mice.

Species-specific CD155 protein expression analysis in wild-type and double humanized B-hCD155/hCD112 mice. Spleen-derived dendritic cells and macrophages from peritoneal lavage fluid were isolated from wild-type C57BL/6 (+/+) and heterozygous B-hCD155/hCD112 (H/+) mice and analyzed by flow cytometry using species-specific anti-CD155 antibodies. Murine CD155 protein was detected in wild-type and heterozygous B-hCD155/hCD112 mice, while human CD155 protein was only detected in B-hCD155/hCD112 mice.