Basic Information

Strain Name
C57BL/6-Cd155tm1(CD155)/Bcgen
Common Name
B-hCD155 mice
Catalog number
110759
Background
C57BL/6J
Related Genes
PVR, HVED, NECL5, Necl-5, PVS, TAGE4
NCBI Gene ID

mRNA Expression Analysis

Species-specific CD155 expression analysis in wild-type and humanized B-hCD155 mice. Splenocytes were collected from wild-type (+/+) and homozygous B-hCD155 mice and analyzed by RT-PCR for CD155 mRNA expression. Human CD155 mRNA was exclusively detected in homozygous B-hCD155 mice compared to wild-type mice.

Protein Expression Analysis

Species-specific CD155 expression analysis in humanized B-hCD155 mice. Macrophages derived from peritoneal lavage were collected from wild-type C57BL/6 (+/+) and homozygous B-hCD155 (H/H) mice and analyzed by flow cytometry using species-specific anti-CD155 antibodies. Human CD155 was exclusively detected in homozygous B-hCD155 mice compared to wild-type mice.