Basic Information

Strain Name
C57BL/6-Cd44tm1(CD44)/Bcgen
Stock Number
110961
Common Name
B-hCD44 mice
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Aliases
CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
Species
C57BL/6J
Appearance
Black
Genotypes
Heterozygous
NCBI Gene ID

Details

Generation of gene editing mouse model and phenotypic analysis

Strain specific CD44 expression analysis in heterozygous B-hCD44 mice by flow cytometry. Splenocyte were collected from C57BL/6 and heterozygous B-hCD44 mice, and analyzed by flow cytometry with anti-CD44 antibody. Mouse CD44 was detectable in C57BL/6 and heterozygous B-hCD44 mice. Human CD44 was exclusively detectable in heterozygous B-CD44 mice but not WT mice.

Strain specific CD44 expression analysis in heterozygous B-hCD44 mice by flow cytometry. Splenocyte were collected from C57BL/6 and heterozygous B-hCD44 mice, and analyzed by flow cytometry with anti-CD44 antibody. Mouse CD44 was detectable in C57BL/6 and heterozygous B-hCD44 mice. Human CD44 was exclusively detectable in heterozygous B-CD44 mice but not WT mice.