Basic Information

Strain Name
C57BL/6-Cd93tm1(CD93)/Bcgen
Stock Number
111135
Common Name
B-hCD93 mice
Background
C57BL/6
Related Genes
CD93 (C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4)
Targeting Strategy
The exon 1 of mouse Cd93 gene that encode the extracellular domain was replaced by human CD93 exon 1 in B-hCD93 mice.
NCBI Gene ID

Details

Protein expression analysis

Strain specific CD93 expression analysis in heterozygous B-hCD93 mice by flow cytometry. Bone marrow were collected from wild type and heterozygous B-hCD93 mice (H/+) , and analyzed by flow cytometry with species-specific CD93 antibody. Mouse CD93 was detectable in wild type mice and heterozygous B-hCD93 mice. Human CD93 was exclusively detectable in heterozygous B-hCD93 mice but not in wild type mice.