Basic Information

Strain Name
C57BL/6-Csf1tm1(CSF1) Csf1rtm1(CSF1R)/Bcgen
Stock Number
121109
Common Name
B-hCSF1/CSF1R mice
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Related Genes
MCSF; CSF-1 BANDDOS, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
Species
C57BL/6
Appearance
Black
Genotypes
Homozygous
NCBI Gene ID

Details

Protein expression analysis

Strain specific CSF1 expression analysis in homozygous B-hCSF1/hCSF1R mice by ELISA. Splenocytes were collected from WT and homozygous B-hCSF1/hCSF1R (H/H) mice stimulated with LPS in vivo, and analyzed by ELISA with species-specific anti-CSF1 ELISA kit. Mouse CSF1 was detectable in WT. Human CSF1 was exclusively detectable in homozygous B-hCSF1/hCSF1R but not WT mice.

Strain specific CSF1R expression analysis in homozygous B-hCSF1/hCSF1R mice by flow cytometry. Blood were collected from WT and homozygous B-hCSF1/hCSF1R (H/H) mice, and analyzed by flow cytometry with species-specific anti-CSF1R antibody. Mouse CSF1R was detectable in WT .Human CSF1R was exclusively detectable in homozygous B-hCSF1/hCSF1R but not WT mice.