Basic Information

Strain Name
C57BL/6J-Lgals9tm1(LGALS9)/Bcgen
Common Name
B-hLGALS9 mice
Background
C57BL/6J
Catalog number
112053
Aliases
LGALS9 (LGALS9A; HUAT; LGALS9)
NCBI Gene ID

Targeting strategy

Gene targeting strategy for B-hLGALS9 mice.

The mouse Lgals9 gene that encode the full-length protein were replaced by human LGALS9 counterpart gene in B-hLGALS9 mice.

Protein expression analysis

Strain specific LGALS9 expression analysis in homozygous B-hLGALS9 mice by ELISA. Blood was collected from wild-type mice (+/+) and homozygous B-hLGALS9 mice (H/H), and analyzed by ELISA with species-specific LGALS9 ELISA kit. Mouse LGALS9 was detectable in wild-type mice. Human LGALS9 was exclusively detectable in homozygous B-hLGALS9 mice but not in wild-type mice.

Summary

Protein expression analysis:

Human LGALS9 protein was detectable in B-hLGALS9 mice.

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