Basic Information

Strain Name
C57BL/6-Klrc1tm1(KLRC1)/Bcgen
Stock Number
110041
Common Name
B-hNKG2A mice
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Related Genes
NKG2A, KLRC1
Species
C57BL/6
Appearance
Black
Genotypes
Heterozygous
NCBI Gene ID

Details

Protein expression analysis in NK cells

Strain specific NKG2A expression analysis in heterozygous B-hNKG2A mice by flow cytometry. Splenocytes were collected from WT and heterozygous B-hNKG2A (H/+) mice, and analyzed by flow cytometry with species-specific NKG2A antibody. Mouse NKG2A was detectable in WT mice and heterozygous B-hNKG2A. Human NKG2A was exclusively detectable in heterozygous B-hNKG2A but not WT mice. (Monalizumab was used to detect the human NKG2A protein in WT and heterozygous B-hNKG2A mice)