Gene targeting strategy for B-hPD-L1/hCD40 mice. The exon 3 of mouse Pd-l1 gene that encodes the extracellular domain was replaced by human PD-L1 exon 3 and the exons 2-7 of mouse Cd40 gene that encode the extracellular domain were replaced by human CD40 exons 2-7 in B-hPD-L1/hCD40 mice.
- Clin Cancer Res 2016; published online Nov 8. DOI:10.1158/1078-0432.CCR-16-1741
- Blood First Edition paper, May 11, 2010; DOI 10.1182/blood-2010-02-271874.
- J Immunol published online 1 May 2017. doi:10.4049/jimmunol.1601490