Basic Information

Strain name
C57BL/6-Pdgfrbtm1(PDGFRB)/Bcgen
Common name
B-hPDGFRB mice
Background
C57BL/6
Catalog number
111317
NCBI Gene ID
Aliases
CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT

mRNA expression analysis

Strain specific analysis of PDGFRB gene expression in wild type and B-hPDGFRB mice by RT-PCR.

Mouse Pdgfrb mRNA was detectable only in lung of wild type (+/+) mice. Human PDGFRB mRNA was detectable only in homozygous B-hPDGFRB (H/H) mice but not in wild type mice.

Protein expression analysis

Strain specific PDGFRB expression analysis in homozygous B-hPDGFRB mice by western blot.

Lung was collected from wild type (+/+) mice and homozygous B-hPDGFRB (H/H) mice and analyzed by western blot with species-specific anti-PDGFRB antibody. Mouse PDGFRB was detectable in wild type mice. Human PDGFRB was detectable in homozygous B-hPDGFRB but not in wild type mice.