Basic Information
Strain name
C57BL/6-Pdgfrbtm1(PDGFRB)/Bcgen
Common name
B-hPDGFRB mice
Background
C57BL/6N
Catalog number
111317
NCBI Gene ID
Aliases
CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT
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mRNA expression analysis
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Species-specific PDGFRB gene expression analysis in wild-type and humanized B-hPDGFRB mice by RT-PCR. Murine Pdgfrb mRNA was detected in lung tissue isolated from wild-type (+/+) mice, while human PDGFRB mRNA was detected in homozygous B-hPDGFRB (H/H) mice.
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Protein expression analysis
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Species-specific PDGFRB protein expression analysis in wild-type and humanized B-hPDGFRB mice. Lung tissue was isolated from wild-type C57BL/6 (+/+) mice and homozygous B-hPDGFRB (H/H) mice and analyzed by western blot using species-specific anti-PDGFRB antibodies. Murine PDGFRB protein was detected in wild-type mice, while human PDGFRB protein was detected in B-hPDGFRB mice.
