Basic Information

Strain Name
C57BL/6-Psgl-1tm1(PSGL-1)/Bcgen
Stock Number
111470
Common Name
B-hPSGL-1 mice
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Related Genes
SELPLG (CLA; CD162; PSGL1; PSGL-1)
Species
C57BL/6
Appearance
Black
Genotypes
Heterozygous
NCBI Gene ID

Details

Generation of gene editing mouse model and phenotypic analysis

Strain specific PSGL-1 expression analysis in heterozygous B-hPSGL-1 mice by flow cytometry. Splenocyte were collected from WT and heterozygous B-hPSGL-1 mice, and analyzed by flow cytometry with anti-PSGL-1 antibody. Mouse PSGL-1 was detectable in WT mice and heterozygous B-hPSGL-1 mice. Human PSGL-1 was exclusively detectable in heterozygous B-hPSGL-1 mice but not WT mice.