Basic Information

Strain name
C57BL/6-Selptm1(SELP)/Bcgen
Common Name
B-hSELP mice
Background
C57BL/6
Catalog Number
110836
Aliases
SELP (CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL)
NCBI Gene ID

Targeting strategy

Gene targeting strategy for B-hSELP mice.

The exons 3-13 of mouse Selp gene that encode the extracellular region were replaced by human SELP exons 3-14 in B-hSELP mice.

Protein expression analysis

Strain specific SELP expression analysis in homozygous B-hSELP mice by ELISA. Serum were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hSELP mice (H/H), and analyzed by ELISA with species-specific SELP ELISA kit. Mouse SELP was detectable in wild-type mice. Human SELP was exclusively detectable in homozygous B-hSELP but not wild-type mice.

Summary

Protein expression analysis:

Mouse SELP was detectable in wild-type mice. Human SELP was exclusively detectable in homozygous B-hSELP but not wild-type mice.