Basic Information

Strain name
C57BL/6-Selptm1(SELP)/Bcgen
Common Name
B-hSELP mice
Background
C57BL/6J
Catalog Number
110836
Aliases
SELP (CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL)
NCBI Gene ID

Gene targeting strategy

Gene targeting strategy for B-hSELP mice. The exons 3-13 of mouse Selp gene that encode the extracellular region were replaced by human SELP exons 3-14 in B-hSELP mice.

Protein expression analysis

Species-specific SELP protein expression analysis in humanized B-hSELP mice. Serum was collected from wild-type C57BL/6 (+/+) and homozygous B-hSELP (H/H) mice, and analyzed by ELISA using species-specific SELP kits. Murine SELP protein was detected in wild-type mice, while human SELP protein was detected in B-hSELP mice.