Basic Information

Strain Name
C57BL/6-Siglecgtm2(SIGLEC10)/Bcgen
Stock Number
110843
Common Name
B-hSIGLEC10 mice
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Related Genes
SIGLEC-10, SLG2, Siglecg
Species
C57BL/6N
Appearance
Black
Genotypes
Heterozygous
NCBI Gene ID

Protein Expression Analysis

Protein expression analysis in B cells

Species-specific SIGLEC10 protein expression analysis in humanized B-hSIGLEC10 mice. Splenocytes were isolated from wild-type C57BL/6 (+/+) and heterozygous B-hSIGLEC10 (H/+) mice, and analyzed by flow cytometry using species-specific SIGLEC10 antibodies. Murine SIGLEC10 protein was detected in wild-type and heterozygous B-hSIGLEC10 mice, while human SIGLEC10 protein was exclusively detected in humanized B-hSIGLEC10 mice.

Protein expression analysis in macrophages

Species-specific SIGLEC10 protein expression analysis in humanized B-hSIGLEC10 mice. Splenocytes were isolated from wild-type C57BL/6 (+/+) and heterozygous B-hSIGLEC10 (H/+) mice, and analyzed by flow cytometry using species-specific SIGLEC10 antibodies. Murine SIGLEC10 protein was detected in wild-type and heterozygous B-hSIGLEC10 mice, while human SIGLEC10 protein was exclusively detected in humanized B-hSIGLEC10 mice.