Basic Information

Strain Name
C57BL/6-Tlr8tm1(TLR8)/Bcgen
Common Name
B-hTLR8 mice
Background
C57BL/6
Catalog Number
110104
Aliases
toll-like receptor 8, CD288
NCBI Gene ID

Expression analysis in dendritic cells

Splenocytes were collected from WT and homozygous B-hTLR8 (H/H) mice, and analyzed by flow cytometry with species-specific anti-TLR8 antibody. Mouse TLR8 was detectable in WT and homozygous B-hTLR8 mice compared to isotype due to the cross-reactivity of the anti-mTLR8 antibody between mice and humans.. Human TLR8 was exclusively detectable in homozygous B-hTLR8 mice compared to WT.

Splenocytes were collected from WT and homozygous B-hTLR8 (H/H) mice, and analyzed by flow cytometry with species-specific anti-TLR8 antibody. Mouse TLR8 was detectable in WT and homozygous B-hTLR8 mice compared to isotype due to the cross-reactivity of the anti-mTLR8 antibody between mice and humans.. Human TLR8 was exclusively detectable in homozygous B-hTLR8 mice compared to WT.

Expression analysis in monocytes

Splenocytes were collected from WT and homozygous B-hTLR8 (H/H) mice, and analyzed by flow cytometry with species-specific anti-TLR8 antibody. Mouse TLR8 was detectable in WT and homozygous B-hTLR8 mice compared to isotype due to the cross-reactivity of the anti-mTLR8 antibody between mice and humans. Human TLR8 was exclusively detectable in homozygous B-hTLR8 mice compared to WT.

Splenocytes were collected from WT and homozygous B-hTLR8 (H/H) mice, and analyzed by flow cytometry with species-specific anti-TLR8 antibody. Mouse TLR8 was detectable in WT and homozygous B-hTLR8 mice compared to isotype due to the cross-reactivity of the anti-mTLR8 antibody between mice and humans. Human TLR8 was exclusively detectable in homozygous B-hTLR8 mice compared to WT.

Expression analysis in T cells

Splenocytes were collected from WT and homozygous B-hTLR8 (H/H) mice, and analyzed by flow cytometry with species-specific anti-TLR8 antibody. Mouse TLR8 was detectable in WT and homozygous B-hTLR8 mice compared to isotype due to the cross-reactivity of the anti-mTLR8 antibody between mice and humans. Human TLR8 was exclusively detectable in homozygous B-hTLR8 mice compared to WT.