Basic Information
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Details
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Protein expression analysis (F2)
Strain specific LILRB2 expression analysis in transgenic B-Tg(hLILRB2-hLILRB3) mice by flow cytometry. Granulocytes of blood were collected from wild-type mice (+/+) and transgenic B-Tg(hLILRB2-hLILRB3) mice (Tg), and analyzed by flow cytometry with species-specific anti-human LILRB2 antibody. Human LILRB2 was detectable in granulocytes from B-Tg(hLILRB2-hLILRB3) mice but not wild-type mice.
Strain specific LILRB2 expression analysis in transgenic B-Tg(hLILRB2-hLILRB3) mice by flow cytometry. Dendritic cells derived from bone marrow were collected from wild-type mice (+/+) and transgenic B-Tg(hLILRB2-hLILRB3) mice (Tg), and analyzed by flow cytometry with species-specific anti-human LILRB2 antibody. Human LILRB2 was detectable in dendritic cells from B-Tg(hLILRB2-hLILRB3) mice but not in wild-type mice.
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Summary
LILRB2 protein expression:
1.Detectable in dendritic cells derived from bone marrow. (F2)
2.Detectable in blood cells. (F2)
3.Detectable in B cells, dendritic cells and macrophages from blood. (F3)
LILRB3 protein expression:
1.Detectable in dendritic cells derived from bone marrow. (F2)
2.Detectable in T cells, B cells, dendritic cells and macrophages from blood. (F3)