Basic Information

Strain name
C57BL/6-TgTn(LILRB2-LILRB3)1/Bcgen
Common name
B-Tg(hLILRB2-hLILRB3) mice
Catalog number
110858
Background
C57BL/6N
Aliases
LILRB2: ILT4, LIR2, CD85D, ILT-4, LIR-2, MIR10, MIR-10 LILRB3: HL9, ILT5, LIR3, PIRB, CD85A, ILT-5, LIR-3, PIR-B, LILRA6

Details

Protein expression analysis (F2)

Strain specific LILRB2 expression analysis in transgenic B-Tg(hLILRB2-hLILRB3) mice by flow cytometry. Granulocytes of blood were collected from wild-type mice (+/+) and transgenic B-Tg(hLILRB2-hLILRB3) mice (Tg), and analyzed by flow cytometry with species-specific anti-human LILRB2 antibody. Human LILRB2 was detectable in granulocytes from B-Tg(hLILRB2-hLILRB3) mice but not wild-type mice.

Strain specific LILRB2 expression analysis in transgenic B-Tg(hLILRB2-hLILRB3) mice by flow cytometry. Dendritic cells derived from bone marrow were collected from wild-type mice (+/+) and transgenic B-Tg(hLILRB2-hLILRB3) mice (Tg), and analyzed by flow cytometry with species-specific anti-human LILRB2 antibody. Human LILRB2 was detectable in dendritic cells from B-Tg(hLILRB2-hLILRB3) mice but not in wild-type mice.

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Summary

LILRB2 protein expression:

1.Detectable in dendritic cells derived from bone marrow. (F2)

2.Detectable in blood cells. (F2)

3.Detectable in B cells, dendritic cells and macrophages from blood. (F3)

LILRB3 protein expression:

1.Detectable in dendritic cells derived from bone marrow. (F2)

2.Detectable in T cells, B cells, dendritic cells and macrophages from blood. (F3)