Basic Information

Common name
B-Luc-EGFP HL-60
Catalog number
Acute myelogenous leukemia
Tissue types
Peripheral blood
Peripheral blood

Targeting Strategy

Gene targeting strategy for B-Luc-EGFP HL-60 cells. The CMV promoter and luciferase-EGFP were inserted into the targeting vector by lentivirus.

Phenotypic Analysis

Luminescence signal intensity of B-Luc-EGFP HL-60 cells. B-Luc-EGFP HL-60 cells displayed strong luminescence signal intensity compared to HL-60 cells, as detected by the Bright-GloTM luciferase Assay system (Promega, Cat E2610).

In Vivo Imaging Analysis

Tumor growth and in vivo imaging of B-Luc-EGFP HL-60 cells. B-Luc-EGFP HL-60 cells (1×105) were injected by tail vein into B-NDG mice. (A) Imaging was performed twice a week for tumor detection and signal intensity analysis. (B) Body weight was measured twice a week (Mean ± SEM). Altogether these data indicate that B-Luc-EGFP HL-60 cells can be used for in vivo efficacy evaluation.

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