Basic Information
Common name
B-luc EL4
Catalog Number
310682
Aliases
NA
Disease
Lymphoma
Organism
Mouse
Strain
C57BL/6
Tissue types
Lymphoma
Tissue
T lymphocyte
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Targeting Strategy
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Gene targeting strategy for B-luc EL4. The luciferase cDNA sequence with CAG promoter was inserted in the ROSA26 intron1 of wild-type EL4.
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In Vivo Imaging Analysis
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Tumor growth and in vivo imaging of B-luc EL4 cells. B-luc EL4 cells (2×105) were injected by tail vein into C57BL/6 mice (female, 7-8 week-old, n=5). (A) Imaging was performed on days 0, 3, 6, 10, 13, 17, 20, 24 and 27 for tumor detection and signal intensity analysis. (B) Body weight was measured twice a week (Mean ± SEM). Altogether these data indicate that B-luc EL4 cells can be used for in vivo efficacy evaluation.
