Basic Information
Common Name
B-luc MIA PaCa-2
Catalog Number
310674
Aliases
NA
Disease
Pancreas carcinoma
Organism
Human
Strain
NA
Tissue types
Bone marrow
Tissue
Bone marrow
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Targeting Strategy
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Gene targeting strategy for B-luc MIA PaCa-2. The stop-CAG-Pr-luciferase-PA- LoxP-PuroR- LoxP sequence was inserted in the AAVS1 locus of wild-type MIA PaCa-2.
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In Vivo Imaging Analysis
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Tumor growth and in vivo imaging of B-luc MIA PaCa-2 cells. B-luc MIA PaCa-2 cells were subcutaneously inoculated into BALB/c nude mice. Following growth, subcutaneous tumors were excised into small pieces and transplanted into the pancreas of BALB/c nude mice, in situ. (A) Imaging was performed on days 7, 13, 17, 24 and 31 for tumor detection and signal intensity analysis. (B) Body weight was measured twice a week (Mean ± SEM). Altogether these data indicate that B-luc MIA PaCa-2 cells can be used for in vivo efficacy evaluation.
