Basic Information

Strain name
C57BL/6-Mslntm1(MSLN)/Bcgen
Common Name
B-hMSLN mice
Background
C57BL/6
Catalog Number
111129
Aliases
MPF, SMRP
NCBI Gene ID

Targeting strategy

Gene targeting strategy for B-hMSLN mice. The mouse Msln gene sequences that encode the full length of coding region were replaced by human MSLN coding gene sequence in B-hMSLN mice.

Protein expression analysis

Strain specific MSLN protein expression analysis in wild-type mice and B-hMSLN mice by western blotting. Mouse MSLN was detectable in heterozygous B-hMSLN mice (H/+) and wild-type mice (+/+). Human MSLN was detectable only in B-hMSLN mice (H/+).

Summary

Protein expression analysis:

Human MSLN was detectable only in B-hMSLN mice (H/+).