Basic Information

Strain Name
C57BL/6-Nectin4tm2(NECTIN4)/Bcgen
Common Name
B-hNECTIN4 mice
Background
C57BL/6
Catalog number
111702
Aliases
LNIR; PRR4; EDSS1; PVRL4; nectin-4
NCBI Gene ID

mRNA expression analysis

Species-specific NECTIN4 gene expression analysis in wild-type and humanized B-hNECTIN4 mice by RT-PCR. Murine Nectin4 mRNA was detected in lung tissue isolated from wild-type C57BL/6 (+/+) mice, while human NECTIN4 mRNA was detected in homozygous B-hNECTIN4 (H/H) mice.

Protein expression analysis

Species-specific NECTIN4 protein expression analysis in wild-type and humanized B-hNECTIN4 mice. Human NECTIN4 protein was only detected in lung and stomach tissue isolated from homozygous B-hNECTIN4 (H/H) mice by western blot analysis using an anti-human NECTIN4 antibody.