Basic Information
Strain Name
C57BL/6-Plautm1(PLAU)/Bcgen
Common Name
B-hPLAU mice
Background
C57BL/6N
Catalog number
111088
Aliases
ATF; QPD; UPA; URK; u-PA; BDPLT5
NCBI Gene ID
-
mRNA expression analysis
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Species-specific PLAU expression analysis in wild-type and humanized B-hPLAU mice by RT-PCR and western blot. (A) Murine Plau mRNA was detected in kidney tissue isolated from wild-type (+/+) mice, while human PLAU mRNA was exclusively detected in homozygous B-hPLAU (H/H) mice. (B) Liver and kidney tissues were isolated from wild-type C57BL/6 (+/+) and homozygous B-hPLAU (H/H) mice, and analyzed by western blot using an anti-m/hPLAU antibody. PLAU protein was detected in wild-type and B-hPLAU mice due to the cross-reactive antibody.
